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What Are Magic Mushrooms? Some kinds of mushrooms contain psilocybin and psilocyn, substances that can cause hallucinations. Used in large enough doses, these mushrooms have effects similar to the drug LSD. Psilocybin Half-LifeHalf life of psilocybin is about 2.5 hours. This means that it takes about 2.5 hours for the drug’s presence to be reduced by half within your system.How Long Do the Effects of Psilocybin Last?The effects of psilocybin generally last about 6 hours...

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